Inflammatory bowel disease, high blood pressure, and cancer have one vitamin deficiency in common The common factor is vitamin D deficiency. When considering that vitamin D is involved in the regulation of inflammation, it is likely that a deficiency of vitamin D can have an affect on the above mentioned conditions. It is also interesting to notice that vitamin D deficiencies are very common and are likely to go undiagnosed. Most doctors don’t consider testing for such deficiencies unless they have followed up on the latest research regarding vitamin D. Because vitamin D is produced from exposure to sunlight, this type of deficiency is usually caused by decreased exposure due to clothing and the use of sunscreen. A recent study conducted in France found that 99% of the women tested had levels of vitamin D below the threshold set by the researchers and 72.6% of these women had symptoms (Belaid S et al, 2007). When a vitamin D analogue called kh1060 was investigated for its ability to decrease tumor necrosis factor alpha (TNF- alpha) an inflammatory marker in patients with inflammatory bowel disease, it showed the ability to inhibit TNF-alpha (Stio M. et al., 2006). The researchers concluded that it was strong evidence that vitamin D status could be an important regulator of immunity in inflammatory bowel disease. In a very recent study, it was concluded that systolic blood pressure was inversely associated with serum vitamin D concentration in non-hypertensive white persons in the United States (Judd SE, et al., 2008). The researchers stated that this provided a rationale for studies on the potential effect of vitamin D supplementation as a method to reduce systolic blood pressure in persons at risk for hypertension (high blood pressure). Vitamin D could also have an influence on the prevention of colorectal cancer. The University of California, San Diego recently conducted a study on vitamin D and colorectal cancer risk. The researchers concluded that evidence suggested a daily intake of 1000-2000 IU of vitamin D3 per day could reduce the incidence of colorectal cancer (Gorham ED, et al, 2007). Vitamin D levels take a while to increase, but it can easily be done by taking vitamin D3 supplements regularly. We have two formulas with vitamin D3 and you will also find it in the multi-vitamin we carry. The two formulas are the BMJ and the separate D3 formula containing 1000IU per tablet. The BMJ has 400IU of Vitamin D3, but a lot of people would benefit from taking an additional 1000 IU of vitamin D3 daily.
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Wishing you the best of health, Didrik
References: Gorham ED, Garland CF, Garland FC, Grant WB, Mohr SB, Lipkin M, Newmark HL, Giovannucci E, Wei M, Holick MF. Optimal vitamin d status for colorectal cancer prevention a quantitative meta analysis. .Am J Prev Med. Mar;32(3):210-6. Belaid S, Martin A, Schott AM, Laville M, Le Goaziou MF. [Hypovitaminosis D among 18-to-49-years-old women wearing concealing clothes, an ignored reality in general practice. Presse Med. 2007 Nov 29. Judd SE, Nanes MS, Ziegler TR, Wilson PW, Tangpricha V. Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination Survey. Am J Clin Nutr. 2008 Jan;87(1): 136-41. Stio M, Martinesi M, Bruni S, Treves C, d’Albasio G, Bagnoli S, Bonanomi AG. Interaction among vitamin D(3) analogue KH 1060, TNF-alpha, and vitamin D receptor protein in peripheral blood mononuclear cells of inflammatory bowel disease patients. Int Immunopharmacol. 2006 July;6(7):1083-92.Epub 2006 Feb 23. |